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Diagn Microbiol Infect Dis ; 101(2): 115344, 2021 Oct.
Article in English | MEDLINE | ID: covidwho-1303485

ABSTRACT

Ventilator associated pneumonia(VAP) is a severe complication that can lead to high mortality when not early identified or when therapy is delayed. The aim of this study was to evaluate procalcitonin(PCT) as a biomarker for VAP development. In total, 73 hospitalized patients with COVID-19 were analyzed. PCT levels greater than 0.975ng/mL were more related to VAP. No association was found for C-reactive protein (CRP). The results show that procalcitonin may be a pertinent biomarker for VAP diagnosis and can be a helpful tool for antibiotic withdrawal.


Subject(s)
Antimicrobial Stewardship/methods , COVID-19/diagnosis , Pneumonia, Ventilator-Associated/diagnosis , Procalcitonin/blood , Adult , Aged , Aged, 80 and over , Anti-Bacterial Agents/therapeutic use , Biomarkers/blood , COVID-19/complications , Female , Humans , Intensive Care Units , Male , Middle Aged , Pneumonia, Ventilator-Associated/complications , Pneumonia, Ventilator-Associated/drug therapy , ROC Curve , SARS-CoV-2 , COVID-19 Drug Treatment
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